Re: [rp-ml] Jaw Bone From Stem Cells

From: Michael Ervin <>
Date: Sat Aug 28 2004 - 01:53:03 EEST


Some of that early work at the University of Texas was done with polymer
coated calcium phosphate. I think there was a business spun off to a San
Antonio company but I donšt know if it survived.

Mike Ervin
M. A. Ervin & Associates
Austin, Texas

From: "David K. Leigh" <>
Date: Fri, 27 Aug 2004 16:41:37 -0500
To: "Blasch, Larry" <>, 'Brock Hinzmann'
Subject: RE: [rp-ml] Jaw Bone From Stem Cells

Early work at the Univ. of Texas using the SLS process worked on these types
of projects. And, as I recall, they were able to implant an RP jawbone into
a monkey with limited success. The body started adapting to it and
depositing calcium on the matrix. There was more work done on a
bio-material, but I'm not sure what ever happened. I think the original
work was done with less than full density polycarbonate.

David K. Leigh (254)933-1000
Harvest Technologies fax(254)298-0125
Rapid Prototyping Services

-----Original Message-----
From: Blasch, Larry []
Sent: Friday, August 27, 2004 3:35 PM
To: 'Brock Hinzmann';
Subject: RE: [rp-ml] Jaw Bone From Stem Cells


I didn't read it until you pointed it out but you are right, a z-corp with
hydroxyapatite cement see link --> might allow you to build
the bone and implant the marrow stem cells to get the bone growth process
started again.

For a full description of the back implant/boon growth procedure check out

Larry Blasch

-----Original Message-----
From: Brock Hinzmann []
Sent: Friday, August 27, 2004 2:10 PM
Subject: Re: [rp-ml] Jaw Bone From Stem Cells

AP wire story out of London reports on a paper in this
week's Lancet medical journal that doctors in Kiel,
Germany, were able to grow in a man's back, from stem
cells, a replacement lower jaw bone that had been lost to
cancer, which they then surgically removed from his back
and reinserted into its proper place. The jaw bone was
grown in a titanium cage implant.

It seems to me that the Bio-plotter or something similar
should be capable of forming the templates in which to
grow tissues from stem cells. Research at Northwestern
University suggests stem cells are triggered to grow into
different types of tissues by the manner in which they are
physically confined. As the nature of which type of
confinement produces which type of tissue is discovered,
perhaps simple 3-D plotters could shape any tissue to
custom dimensions. Even if the doctors remained
constrained to growing custom bone implants in tantanium
cages, it seems like RP&M should play a role in creating
the custom titanium forms. Anyone on the rp-ml involved in
any aspect of this development?

Brock Hinzmann
Technology Navigator
SRI Consulting Business Intelligence
+1 (650) 859-4350
Received on Sat Aug 28 00:56:45 2004

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